Patrocles

RNA Type: miRNA

Overview: Patrocles is a database of miRNA-target genes and silencing machinery in seven vertebrates. The database has a tool (Patrocles finder) to determine the DNA sequence polymorphisms (DSP) that influence in miRNA-target gene regulation.

Search Methods:

• Keyword: search by octamer motif, target gene id/position (in Polymorphic targets search); or by miRNA id or position (in two search: Polymorphic targets or miRNA); or by miRNA id/position or by gene position (Polymorphic silencing machinery search); or by SNP id (in all three searches: Polymorphic silencing machinery, miRNA and targets).
• TAG: search by seed type, source (in Polymorphic targets search); or by functional compartment, gene id (in Polymorphic silencing machinery search); or by type of polymorphism (in two searches: Polymorphic silencing machinery and miRNA); or by species, SNP effect/status (in all three searches: Polymorphic silencing machinery, miRNA and targets).

Source: Ensembl, miRBase, UCSC Genome Database, HapMap, SymAtlas, dbSNP, Stranger et al., 2007, Landgraf et al., 2007, Xie et al., 2005.

Information Source: Experimental, In silico annotation.

Information Content: Annotation, Polymorphism, Silencing machinary, SNP, Target gene.

Reference: Hiard et al., 2009; Georges et al., 2006

PubmedID: 19906729.

Year: 2010

Multiple search: Yes

Download: No

Genomic Overview: No

Organism: Homo sapiens (Human), Rattus norvegicus (Norway Rat), Canis familiaris (Dog), Mus musculus (House Mouse), Gallus gallus (Chicken), Bos Taurus (Cattle), Pan troglodytes (Chimpanzee).

Url: http://www.patrocles.org/