miRWalk

RNA Type: miRNA

Overview: miRWalk is a database of human, mouse and rat miRNAs targets. The two modules (predicted and validated targets) have information about pathways, diseases, organs, cell lines, transcription factors and also predicted target gene sites. The validated target module represents includes information from the discontinued Argonaute database (Shahi et al., 2006).

Search Methods:

• Keyword: search by Gene Symbol, microRNA name (only for Common Organs and miRNA literature search).
• TAG: search by Species, Gene regions, Transcript (e.g. longest or all), Prediction Programs (only for Gene Target search), Pathway name (only for Pathway search), disease (only for Disease search), Organ (only for Organ search), Cell Line (only for Cell Line search), OMIM Disorder (only for OMIM Disorder search - Online Mendelian Inheritance in Man).
• Tabular: search by proteins involved in processing of miRNA.

Source: miRWalk algorithm result, Target Prediction Tools (e.g. RNA22, miRanda, miRDB, TargetScan, RNAhybrid, PITA, PICTAR and Diana-microT), OMIM, Literature, Argonaute database.

Information Source: Experimental, In silico annotation.

Information Content: Annotation, Binding site, Cell line, Disease, Mammalian microRNA, OMIM Disorders target, Organ, Pathway, Processing Proteins, Target gene, Target miRNA.

Reference: Bhartiya et al., 2011

PubmedID: 16381827.

Year: 2011

Multiple search: Yes

Download: No

Genomic Overview: No

Organism: Homo sapiens (Human), Rattus norvegicus (Norway Rat), Mus musculus (House Mouse).

Url: http://www.ma.uni-heidelberg.de/apps/zmf/mirwalk/