Overview: CircNet used transcriptome sequencing datasets to systematically identify the expression of circRNAs (including known and newly identified by their in-house pipeline) in 464 RNA-seq samples. The database provides the following resources: (i) novel circRNAs, (ii) integrated miRNA-target networks, (iii) expression profiles of circRNA isoforms, (iv) genomic annotations of circRNA isoforms (e.g. 282,948 exon positions), and (v) sequences of circRNA isoforms. CircNet databasealso provides tissue-specific circRNA expression profiles and circRNA-miRNA-gene regulatory networks. It generates an integrated regulatory network that illustrates the regulation between circRNAs, miRNAs and genes.