Overview: miRnalyze is an online web based tool that has been developed to analyse the putative regulation of cell signaling pathways by microRNAs. Genes and pathways data have been adapted from Kyoto Encyclopedia of Genes and Genomes (KEGG) database. MicroRNA target prediction data are retrieved from TargetScanHuman 7.1 target prediction tool. miRnalyze predicts putative miRNA targets in cellular signaling pathways directly through identifying involved genes in those pathways. Additionally, it provides users with the ability to identify common miRNAs that have more than one target in the signal transduction pathways – a feature that is unique to miRnalyze. Further, the tool allows users to sort the enlisted miRNAs based on their type of seed matches and the TargetScan Context++ score. The results thereby displayed in a hierarchy of manner allowing user to identify most relevant miRNAs on top of the lists.
Keyword: Search for pathways names, genes names or microRNAs names